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Two Indian drugmakers seek to end Merck's molnupiravir trials for moderate COVID-19


An experimental COVID-19 therapy tablet known as molnupiravir being developed by Merck & Co Inc and Ridgeback Biotherapeutics LP, is seen on this undated handout picture launched by Merck & Co Inc and obtained by Reuters Could 17, 2021. Merck & Co Inc/Handout by way of REUTERS

BENGALURU, Oct 8 (Reuters) – Two Indian drugmakers Aurobindo Pharma Ltd (ARBN.NS) and MSN Laboratories need to discontinue their respective late-stage trials of Merck & Co’s (MRK.N) experimental antiviral drug molnupiravir in average COVID-19 sufferers.

Each the pharmaceutical companies, nonetheless, will proceed their separate trials in delicate COVID-19 sufferers, in accordance with a statement by the Indian drug regulator’s skilled committee on Friday.

Merck had signed a voluntary licensing pact with Aurobindo Pharma for the oral drug molnupiravir, earlier this 12 months. Aurobindo Pharma has been conducting a medical trial of molnupiravir in 100 sufferers with average COVID-19 since August this 12 months. (https://bit.ly/2WYn61G)

Molnupiravir has proven no important efficacy in opposition to average COVID-19 circumstances, a drug regulator supply instructed Reuters individually. read more

The drug regulator has not but taken a name on the eight firms which have utilized for a molnupiravir licence, the supply added.

A joint trial for the antiviral drug is at the moment being performed by 5 Indian generic drugmakers solely in delicate COVID-19 sufferers in an outpatient setting.

In July, earlier this 12 months, pharmaceutical firm Hetero had introduced interim information from a late-stage trial in delicate COVID-19 sufferers and submitted an utility for emergency use approval for a similar.

Reporting by Shivani Singh in Bengaluru and Neha Arora in New Delhi; Enhancing by Rashmi Aich

Our Requirements: The Thomson Reuters Trust Principles.



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